Shythdf2
WebFigure 2 . YTHDF2 inhibited the activity of endometrial cell. (A,B) qRT-PCR and immunoblot analysis of YTHDF2 in endometrial cell HEC-1-A transfected with lentiviral shControl, YTHDF2 shRNA #1 or #2 as indicated for 72 h.(C,H) Cell proliferation measured by CCK8 assay of HEC-1-A cells stably expressing shYTHDF2 (C) or YTHDF2 (H) as indicated.The … http://www.jinpanmed.cn/archives/date/2024/04/14
Shythdf2
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WebNov 23, 2024 · Moreover, shYTHDF2 markedly triggered cell apoptosis and dysregulation of apoptotic proteins (Fig.2C). On the contrary, YTHDF2 overexpression resulted in reduced … WebFig. 7 LXRalpha and HIVEP2 are functionally essential targets of YTHDF2 in cell proliferation, invasion, cholesterol dysregulation, and tumorigenesis of GBM cells. a Western blotting of …
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WebFeb 15, 2024 · 该研究揭示SUMO化修饰是m6A修饰阅读蛋白YTHDF2功能调控的一个新分子机制,并阐明了其在肿瘤发生中的重要作用。. RNA是遗传信息从DNA传递到蛋白质的关 … WebNov 18, 2024 · YTHDF2 inhibits IL-11 and Serpin E2 expression in HCC cells. (a) Volcano plots showing up (red) - or down (blue) -regulated genes in SMMC7721-shYTHDF2 versus …
Web(C) RT-qPCR analysis of MYC mRNA expression relative to GAPDH of mRNA from shYTHDF2 TNBC, HR+ and HER2+ breast cancer cell lines. (D) Cumulative distribution of …
WebMar 23, 2024 · Nature 子刊 客户文章:m6A 修饰参与调控急性缺血卒中恢复的作用机制,采用MeRIP-Seq高通量测序发现,在急性缺血卒中(Acute Ischemic Stroke, AIS)患者的梗死周围皮质组织和动物模型中,mRNA的m6A修饰水平相比对照组显著提高,作者在其中筛选得到了Plpp3(编码促进卒中动物模型血管修复的LPP3蛋白) the hare tunbridge wells menuWeb100 of cultured RGC s treated by shYthdf2 (Fig ure 1C,D ; Figure 1 v figure supplement 1G,H ). In contrast, 101 the dendrite branching of RGCs with YTHDF1 KD using shYthdf1 was not significantly different from 102 control shRNA ( Figure 1 v figure supplement 1 I), while YTHDF3 KD using shYthdf3 caused a slight the hare \u0026 hounds tetburyWebFeb 10, 2024 · Then shYTHDF2 groups were subsequently overexpressed with MCM2 and MCM5 (shY2+OE-M2/5), with (or without) overexpression of WT/S263A YTHDF2. All the … the bay episode 6WebFeb 12, 2024 · Four stable H1299 cell lines (control, sh-YTHDF2, shYTHDF2-WT and shYTHDF2-K 571 R) were injected into the flanks of nude mice subcutaneously. Being … the bay episode 5WebYTHDF2, also named as YTH domain-containing family protein 2, is a 579 amino acid protein, which contains 1 YTH domain. YTHDF2 specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a … the hare wine coWebJun 21, 2024 · Author summary Epstein–Barr virus (EBV) is a ubiquitous oncogenic virus that contributes to approximately 2% of all cancers by modulating a myriad of host cell activities. M6A is the most abundant RNA modification which is important for infection with HIV-1, HCV, Zika virus, KSHV and SV40 virus. The role of m6A modification and the … the hare\u0027s self sacrifice summaryWebshRNA Plasmid. shRNA Lentiviral Particles. Description. 10 µM, 50-100 transfections. siRNA products generally consist of pools of three to five target-specific 19-25 nt siRNAs designed to knockdown gene expression. for independent verification of YTHDF2 gene silencing results, individual siRNA duplex components are also available upon request. the bay episode 1