Anidulafungin significantly differs from other antifungals in that it undergoes chemical degradation to inactive forms at body pH and temperature. Because it does not rely on enzymatic degradation or hepatic or renal excretion, the drug is safe to use in patients with any degree of hepatic or renal impairment. Volume of distribution: 30–50 L. Webb1 dec. 2009 · Anidulafungin has been studied for other indications. A double-blind trial has compared intravenous anidulafungin with oral fluconazole in 601 patients with …

Anidulafungin Uses, Side Effects & Warnings - Drugs.com

WebbAnidulafungin is an uncrystalline powder with a pKa of 9.46 and is insoluble in water. The solubility of Anidulafungin decreases further strongly when the pH is below 4. WebbAfter addition of anidulafungin, pH of solution was adjusted with sodium hydroxide to approximately 7.0 and mixed until complete dissolution. The obtained solution was then … how to reset iphone 6s without apple id

Food and Drug Administration

WebbAnidulafungin 14 (Table 1) was approved for use in the treatment of O. candidiasis, candidaemia, peritonitis and intraabdominal abscesses due to Candida spp. 57 It is … Webbof Anidulafungin is C58H73N7O17 and molecular weight is 1140.2369. Anidulafungin undergoes slow chemical degradation at physiologic temperature and ph to a ring … Webbmannitol, polysorbate 80, tartaric acid, sodium hydroxide (for pH-adjustment) (see section 2 “Anidulafungin contains sodium”), concentrated hydrochloric acid (for pH-adjustment) … north carolina wind pool insurance