Mitf protein atlas

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Web13 sep. 2002 · In human and mouse, cAMP plays a key role in the control of pigmentation. cAMP, through the activation of protein kinase A, increases the expression of microphthalmia-associated transcription factor (MITF), which in turn stimulates tyrosinase gene expression, to allow melanin synthesis. Beyond this … Webprotein_coding_gene Location ... Waardenburg's syndrome; and familial melanoma. Orthologous to human MITF (melanocyte inducing transcription factor). Genome Resources. Alliance ; Gene:30080 ; VEGA:OTTDARG00000019915 ; Ensembl(GRCz11):ENSDARG00000003732 ; Note None Comparative ... Expression …

MITF reprograms the extracellular matrix and focal adhesion in

WebGene information about ENSG00000187098 / MITF - microphthalmia-associated transcription factor We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. WebMITF is a basic helix-loop-helix leucine zipper transcription factor involved in lineage-specific pathway regulation of many types of cells including melanocytes, osteoclasts, and mast cells. [5] The term "lineage-specific", since it relates to MITF, means genes or traits that are only found in a certain cell type. gods of egypt fmovies

MITF - Antibodies - The Human Protein Atlas

WebOverview of the celline expression of MITF. Protein detected at medium/high level in 4 cell lines. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. ... The Human Protein Atlas project is funded WebProduct Description Polyclonal Antibody against Human MITF Alternative Gene Names bHLHe32, MI, WS2, WS2A Open Datasheet Price $505.00 Product Number HPA003259 Unit Size Concentration 0.1 mg/ml Availability >10 in Stock Ships Ready to Ship Share by E-mail Add to Cart Show all images [5 pictures] Web30 nov. 2024 · A tetracycline-inducible MITF melanoma cell line displayed greater Wnt reporter gene activity following MITF induction, in a manner dependent on crucial endosome trafficking protein Vps27 . Furthermore, MITF induction in C32 melanoma cells caused colocalization of Axin1, the scaffold for the β-catenin destruction complex, with vesicular ... book lair

Brain tissue expression of MITF - Summary - The Human Protein …

MiTF/TFE Family of Transcription Factors: Master Regulators of ...

WebMiTF is Associated with Chemoresistance to Cisplatin in A549 Lung ... containing PMSF (Sigma-Aldrich) and protease inhibitors (Thermo Fisher Scientific, Waltham, MA, USA). The protein concentrations of cell lysates were determined by the BCA Assay Kit (Bio-Rad ... We analyzed the lung patients’ data from The Cancer Genome Atlas ... http://genome.cse.ucsc.edu/cgi-bin/hgGene?hgsid=1604921059_rVn1WbQrVVz6m7V7RtaRB8ojEueA&hgg_section_method_close=1 gods of egypt free to watchWebShowing cell line RNA expression of MITF (bHLHe32, MI, WS2, WS2A). We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. gods of egypt free streaming

"Web6 jul. 2016 · Objective: This study investigated the role and mechanism of action of G protein-coupled estrogen receptor (GPER) in melanogenesis. Methods: GPER expression was detected in the A375 human melanoma cell line and B16 mouse melanoma cell line. Cell proliferation, melanin content, tyrosinase (TYR) activity, cyclic adenosine … " - Mitf protein atlas

Mitf protein atlas

MITF protein expression summary - The Human Protein Atlas

Web28 sep. 2024 · The authors also conducted an in silico analysis using TCGA Pan-Cancer-Atlas data to confirm that patients with MITF-E318K melanoma carriers harboured a common pattern of 9p21.3 deletion. The overall results provided greater insights into the clinical strategies that could be used to manage and treat MITF-associated tumour types. Web5 dec. 2024 · Indeed, MITF functions as a central regulator of melanocyte differentiation and melanogenesis by controlling the transcription of a panel of genes, including melan-A (MART1), tyrosinase and premelanosome protein PMEL17 (PMEL/SILV/gp100) [36,37,38], which encode proteins that have been reported to be tumor-specific antigens [39, 40].

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Web1 apr. 2013 · A transcription factor that activates the transcription of tyrosinase and tyrosinase-related protein 1 (TYRP1), and dopachrome tautomerase (DCT). These are enzymes that are specifically expressed in melanocytes (Yasumoto et al., 1995). For tyrosinase, MITF binds to a symmetrical DNA sequence found in the promoter region: a … WebRabbit polyclonal MITF antibody. 100% Bioguaranteed. US EN. Applications Products Services Support. All Photos (3) SAB4501879. Anti-MITF antibody ... Prestige Antibodies ® Powered by Atlas Antibodies, affinity isolated antibody, buffered ... Anti-MITF Antibody detects endogenous levels of total MITF protein. MITF (microphthalmia-associated ...

Web15 mei 2024 · MITF was found as one of the upstream regulators of p300 target gene expression. D, Number of known MITF target genes that are also included in the p300 downstream effector genes. IPA identified 33 genes from the p300 target gene set as known MITF target genes. Web21 mrt. 2024 · MITF (Melanocyte Inducing Transcription Factor) is a Protein Coding gene. Diseases associated with MITF include Tietz Albinism-Deafness Syndrome and Melanoma, Cutaneous Malignant 8 . Among its …

WebMITF has 5,856 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 87 datasets. Web26 aug. 2024 · 2.1 MITF isoforms The human MITF gene spans approximately 230,000 bp and is located on chromosome 3 (GRCh38/hg38 chr3:69,739,435–69,968,336), whereas the mouse Mitf gene is on chromosome 6 and extends over 215,000 bp (GRCm38/mm10 chr6:97,807,058–98,021,349).

Webhuman brain protein location i The Human brain protein data is based on curated and manually selected Tissue Atlas data. The standard brain regions used in the Tissue …

WebThe following is a partial list of "housekeeping genes." For a more complete and updated list, see HRT Atlas database ... Regulated by MITF) HMGB1 High mobility group box binds DNA; ILF2 Homo sapiens interleukin … bookland co krWeb3 aug. 2015 · Because of the demand on lysosomal function by mitophagy, we investigated a role for the transcription factor EB (TFEB), a master regulator of lysosomal biogenesis, in this process. We show that during mitophagy TFEB translocates to the nucleus and displays transcriptional activity in a PINK1- and Parkin-dependent manner. bookland.com plWeb31 mrt. 2011 · KIT activation up-regulates MITF protein expression. (A) Western blot shows robust increase of MITF protein expression by 24 to 48 hours in primary murine BMMCs treated with SCF (100 ng/mL). Relative expression is calculated by taking the ratio of the densitometry signal for MITF to tubulin and normalizing to 1.0 for the zero time point. bookland bialystokWebMITF (bHLHe32, MI, WS2, WS2A) protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to … gods of egypt film ratedWebCell atlas. Showing subcellular location of MITF (bHLHe32, MI, WS2, WS2A). gods of egypt free movies onlineWebGene information about ENSG00000187098 / MITF - microphthalmia-associated transcription factor We use cookies to enhance the usability of our website. If you … gods of egypt free movie streamWeb21 feb. 2001 · MITF. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 526. Protein existence. Evidence at protein level. Annotation score. 5/5. Entry. ... Efficient DNA binding requires dimerization with another bHLH protein (PubMed:14975237). Binds DNA in the form of homodimer or heterodimer with either … gods of egypt filmed where