Iph4102-201
Web13 sep. 2024 · IPH4102 in PTCL were presented at 2024 International Conference on the Malignant Lymphoma (ICML) in June 2024. o The outcome of the first stage of the MF and PTCL cohorts is expected in the second half of 2024. Initial efficacy data are expected starting in 2024. o Study results from the Phase I dose-escalation and expansion trial of … Web3 apr. 2024 · IPH4102 will be administered every week for 5 weeks then every 2 weeks for 10 administrations then every 4 weeks until disease progression or unacceptable toxicity. … IPH4102 Alone or in Combination With Chemotherapy in Patients With …
Iph4102-201
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Web• Initiation of IPH4102 , an international, openTELLOMAK -label, multicohort Phase II - study evaluating the efficacy and safety of IPH4102 in patient populations larger expressing KIR3DL2, including peripheral T cell lymphoma (PTCL). TELLOMAK is planned to recruit up to 250 patients, with IPH4102 evaluated as a single agent in WebInterpretation IPH4102 is safe and shows encouraging clinical activity in patients with relapsed or refractory cutaneous T-cell lymphoma, particularly those with Sézary syndrome. If confirmed in future trials, IPH4102 could become a novel treatment option for these patients. A multi-cohort, phase 2 trial (TELLOMAK) is underway to confirm
WebStudy of IPH4102 alone or in combination with chemotherapy in patients with Advanced T-cell Lymphoma. A.4.1 Sponsor's protocol code number IPH4102-201 A.5.2 US NCT …
Web20 mei 2016 · IPH4102 is a first-in-class anti-KIR3DL2 monoclonal antibody (mAb). It depletes selectively KIR3DL2-expressing cells. Its modes of action include Antibody-Dependent Cell-Cytoxicity (ADCC) and –Phagocytosis (ADCP). IPH4102 has potent efficacy in non-clinical models, in particular ex vivo autologous assays using primary CTCL cells. Web14 mrt. 2024 · Biological: IPH4102 Study Type Interventional Enrollment (Anticipated) 166 Phase Phase 2 Contacts and Locations This section provides the contact details for …
WebTELLOMAK - IPH4102-201 T-cell Lymphoma Anti-KIR3DL2 Therapy. An Open Label, Multicohort, Multi-center Phase II Study Evaluating the Efficacy and Safety of …
Web13 okt. 2016 · IPH4102 is a first-in-class anti-KIR3DL2 humanized cytotoxicity-inducing antibody, designed to trigger killing of CTCL cancer cells, an orphan disease. This group of rare cutaneous lymphomas of T... c\\u0026w tank cleaningWeb1 aug. 2024 · IPH4102 is a first-in-class monoclonal antibody targeting KIR3DL2, a cell surface protein that is expressed in cutaneous T-cell lymphoma, and predominantly in its … c \\u0026 w\\u0027s flowers \\u0026 giftsWeb15 jun. 2024 · IPH4102 is Innate Pharma’s wholly-owned, first-in-class anti-KIR3DL2 humanized therapeutic antibody, designed to trigger immune cell-mediated killing of CTCL cancer cells. 25 patients, with a median age of 71 years old and a median number of four prior systemic treatments, were evaluable for safety (10 dose levels: 0.0001 to 10 mg/kg). c\u0026w shoes of georgiaWebSézary syndrome (SS), the most aggressive form of cutaneous T-cell lymphoma (CTCL), is characterized by a high expression of the KIR3DL2 receptor. Speaking f... east and west sussex mapWeb12 apr. 2024 · Protocol: IPH4102-201: TELLOMAK: An open label, multi-cohort, multi-center phase II study evaluating the efficacy and safety of IPH4102 alone or in combination with … c\u0026w trailers golden msWeb25 jun. 2024 · IPH4102 is a humanised, first-in-class, monoclonal antibody that targets KIR3DL2, a cell surface protein widely expressed in cutaneous T-cell lymphoma, and … east and west towing kremmling coWeb2 feb. 2024 · IPH4102 Alone or in Combination With Chemotherapy in Patients With Advanced T Cell Lymphoma (TELLOMAK) Latest version (submitted February 2, 2024) … c\\u0026w trailers golden ms