WebRationale and objective: It is well established that stress induces reinstatement of drug seeking in an animal model of relapse. Here we studied the role of the medial prefrontal cortex (mPFC) and orbitofrontal cortex (OFC) in foot-shock stress-induced reinstatement of cocaine seeking. WebAug 1, 2003 · The STRESS CS was established by pairing a continuous white noise (70 dB) with intermittent foot shock (10 min; 0.5 mA; 0.5 s on; mean off period of 40 s). Ethanol dependence was induced by an ...
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WebIt has been convincingly argued by several investigators that locomotor activation is not an experimental confound in the CPP model (Van der Kooy, 1987; Bardo and Bevins, 2000 ). There is also evidence that stressors other than intermittent footshock can reinstate … WebApr 29, 2024 · A punishment model, in which foot-shock is delivered to induce voluntary abstinence from cocaine has been used in at least two studies to date. Following a drug-free period, relapse to drug-seeking is induced by the drug itself (non-contingent cocaine), drug-paired cues, the drug-paired context, or cues+context. iko rubershield eco
Stimulus conditioned to foot-shock stress reinstates alcohol …
WebJan 6, 2011 · Electric foot-shock (0.8 mA, 1-s) was delivered on a variable time schedule at a mean interval of 40 s (10-70 s range). This stress priming procedure was based on a … WebReinstatement of fear, elicited by foot-shock in a neutral environment, was observed for the delayed group but not for the immediate group. By utilizing the passive-avoidance … WebJan 6, 2011 · One of the most commonly used forms of stress for studying this relationship is acute exposures to mild, intermittent, electric footshocks. The ability of footshock stress to induce reinstatement... is the staircase on netflix